![intriguing datum intriguing datum](http://newsimoffer.com/wp-content/uploads/2015/12/Gp-Interesting-Data-Packs.jpg)
Intriguing datum skin#
Physical examination was otherwise normal apart from a clearly swollen left lower extremity accompanied with engorged superficial veins, hyperpigmentation and trophic skin changes.
![intriguing datum intriguing datum](https://cdn.acidcow.com/pics/20210506/1620315927_227h8zli6d.jpg)
No carotid or over the umbilicus bruits were audible and pedal pulses were palpable. His blood pressure was 130/85 mmHg and there were no abnormalities to find in the cardiovascular or respiratory systems. On initial examination, he was afebrile and his pulse rate was 82/min and regular. Otherwise, he did not take any regular medication and he neither smoked tobacco nor drank alcohol. Then the patient had been thoroughly investigated and no specific diagnosis of renal infarct of unknown origin had been made. He also reported a previous history of hospitalization due to an episode of acute left-sided loin pain associated with macroscopic haematuria at the age of 60 years.
![intriguing datum intriguing datum](https://datum.imgix.net/careers/Group.jpg)
He had no significant past medical history apart from an episode of deep vein thrombosis of the left lower extremity four years ago, provoked by a non-displaced fracture of the tibia after a motor vehicle accident. Case PresentationĪ 62-year-old Caucasian male, with no previous ocular or neurological symptoms, experienced a sudden and painless loss of vision in the left eye while swimming. We also discuss the clinical complexity of such a diagnosis as well as we briefly review the current literature regarding similar published case reports. Herein, we aim to present a middle-aged male patient who experienced an episode of severe, painless and unilateral visual loss due to CRAO associated with PFO. CRAO or branch retinal artery occlusion (BRAO) associated with PFO represents an unexpected site of systemic paradoxical embolism that requires high index of clinical suspicion and meticulous laboratory investigation in order to unravel the concealed initial source of thrombus generation. The most important and well-documented clinical manifestation of PFO is the cryptogenic ischemic stroke due to a paradoxical embolus. Congenital cardiac anomalies, such as patent foramen ovale (PFO) may be the source of a paradoxical embolic event, although the majority of patients with PFO follow an uneventful and silent clinical course. Subsequently, the most common risk factors for CRAO include carotid atherosclerosis, cardiac valvular disease and cardiac arrhythmias, mainly atrial fibrillation.
![intriguing datum intriguing datum](https://m.media-amazon.com/images/I/31056J3NgVL._SL500_.jpg)
ĬRAO is usually the result of an embolus, either of cardiac origin or dislodged from an unstable atherosclerotic plaque of carotid bifurcation. Therefore, when CRAO occurs, a severe loss of vision is expected with the exception of cases having an unaffected cilioretinal artery that undertakes the blood supply of the retina and guarantees the restoration of central vision. However, some patients experience transient visual loss due to an impermanent embolic episode which is also known as amaurosis fungax and corresponding to transient ischemic stroke. Central retinal artery occlusion represents the ophthalmic analogue of ischemic stroke and is typically manifested with sudden, severe and painless loss of vision.